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目的 观察红参与葡萄糖酸钙对抗环磷酰胺致小鼠骨质疏松的作用。方法 用环磷酰胺造成骨丢失为主的骨质疏松模型 ,分别用红参和葡萄糖酸钙灌胃预防给药。结果 环磷酰胺可致小鼠骨钙及骨羟脯氨酸含量等比例减少和胸腺萎缩。红参和葡萄糖酸钙对此有明显的防治作用，但后者不能阻止骨羟脯氨酸的减少。结论 红参有明显的对抗环磷酰胺致小鼠骨质疏松的作用。
Objective To observe the effect of red involved calcium gluconate on cyclophosphamide-induced osteoporosis in mice. Methods The model of osteoporosis with bone loss based on cyclophosphamide was administered. Ginseng and calcium gluconate were used for gavage to prevent drug administration. Results Cyclophosphamide could reduce bone calcium and bone hydroxyproline content and thymus atrophy in mice. Red ginseng and calcium gluconate have obvious preventive and therapeutic effects, but the latter cannot prevent the reduction of bone hydroxyproline. Conclusion Red ginseng has obvious anti-cyclophosphamide-induced osteoporosis in mice.