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目的探讨血清超敏C反应蛋白(HsCRP)与血清同型半胱氨酸联合检测对冠心病的预测价值。方法利用胶乳增强免疫比浊法测定血清超敏C反应蛋白,以酶联免疫吸附实验(ELISA)测定血清tHCY。结果稳定性心绞痛(SA)组、不稳定性心绞痛(UA)组和急性心肌梗塞(AMI)组HsCRP、血清同型半胱氨酸水平明显高于健康对照组,且HsCRP与血清同型半胱氨酸呈正相关。结论HsCRP与血清同型半胱氨酸联合检测对冠心病的预防、诊断及预后判断具有重要的临床价值。
Objective To investigate the predictive value of serum homocysteine (HsCRP) and serum homocysteine in the diagnosis of coronary heart disease (CHD). Methods The serum hypersensitive C - reactive protein was detected by latex enhanced turbidimetric method. The level of serum tHCY was measured by enzyme - linked immunosorbent assay (ELISA). Results HsCRP and serum homocysteine levels in stable angina (SA) group, unstable angina pectoris (UA) group and acute myocardial infarction (AMI) group were significantly higher than those in healthy control group, and HsCRP was positively correlated with serum homocysteine Was positively correlated. Conclusion The combination of HsCRP and serum homocysteine has important clinical value in the prevention, diagnosis and prognosis of coronary heart disease.