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目的研究康复新液与质子泵抑制剂(PPI)联合治疗较大消化性溃疡(PU)的疗效。方法将经胃镜检查确诊的43例PU患者随机分为两组,治疗组23例,po康复新液10 mL、每日3次,潘托拉唑注射液40 mg、每日静滴2次;对照组20例,仅以潘托拉唑注射液40 mg、每日静滴2次,两周后评估溃疡愈合情况。结果各项临床症状的改善和疼痛消失情况差异无显著性(P>0.05);胃镜下溃疡愈合率及总有效率均有显著性差异(P<0.05);两组在用药期间,未见不良反应,均有良好的耐受性。结论康复新液联合PPI治疗PU可提高溃疡的愈合率和总有效率,缩短溃疡的愈合时间。
Objective To study the curative effect of Kangfuxin solution and proton pump inhibitor (PPI) in the treatment of larger peptic ulcer (PU). Methods Forty-three patients with PU diagnosed by gastroscopy were randomly divided into two groups: treatment group (23 cases), po Kangfuxin solution (10 mL), three times a day, and pantoprazole injection (40 mg) Control group of 20 patients, only pantoprazole injection 40 mg, intravenous infusion 2 times a day, two weeks after the assessment of ulcer healing. Results There was no significant difference between the improvement of clinical symptoms and the disappearance of pain (P> 0.05). The healing rate and total effective rate of gastric ulcer were significantly different (P <0.05) Reaction, are well tolerated. Conclusion Kangfuxin combined with PPI can improve the healing rate and the total effective rate of ulcer and shorten the healing time of ulcer.