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肾性骨营养不良是慢性肾功能衰竭的严重问题。本文研究试图确定β-阻滞剂是否影响慢性血液透析患者的肾性骨营养不良或甲状旁腺激素(PTH)浓度。本组患者均为进行长期血液透析的慢性肾功能衰竭患者,9例伴有高血压或心绞痛患者从肾功能衰竭发生时就开始服心得安,平均剂量200mg/天,疗程20个月;25例对照组不服心得安。结果表明,服药组血清钙、磷、镁、白蛋白等与对照组无显著区别,但PTH显著降低(P<0.01)。两组PTH浓度均与镁、钙、磷浓度无关,也与透析期或病程无关。服药组硷性磷酸酶浓度显著下降
Renal osteodystrophy is a serious problem of chronic renal failure. This study sought to determine if beta-blockers affect renal osteodystrophy or parathyroid hormone (PTH) concentrations in chronic hemodialysis patients. This group of patients were chronic renal failure patients with long-term hemodialysis, 9 patients with hypertension or angina pectoris started from the onset of renal failure, the average dose of 200mg / day for 20 months; 25 cases The control group was not convinced. The results showed that the medication group serum calcium, phosphorus, magnesium, albumin and the control group no significant difference, but PTH was significantly lower (P <0.01). PTH concentrations in both groups have nothing to do with the concentration of magnesium, calcium, phosphorus, but also with the dialysis or duration has nothing to do. The concentration of alkaline phosphatase in the medication group decreased significantly