目的:分析鼻内镜下手术致鼻中隔穿孔的原因,减少并发症的发生。方法:回顾鼻中隔患者456例,对于传统手术与内镜下手术及同期行鼻窦手术,发生鼻中隔穿孔的并发症进行比较、分析。结果:传统手术与内镜下手术致中隔穿孔无明显差异,同期行鼻窦手术较前两者有明显差异。结论:鼻内镜下中隔矫正同期行鼻窦手术致中隔穿孔的几率较高。把握好同期手术的时机,熟练内镜操作及术后换药,可减少中隔穿孔的发生。 Objective: To analyze the causes of nasal septum perforation caused by endoscopic surgery and reduce the incidence of complications. Methods: 456 patients with nasal septum were retrospectively analyzed. Comparisons and analyzes were made between the complications of traditional surgery and endoscopic surgery and sinus surgery. Results: There was no significant difference in perforation of septum between traditional surgery and endoscopic surgery. There was a significant difference between the two methods in the same period of sinus surgery. Conclusion: Endoscopic sinus surgery in the same period of sinus surgery caused a higher probability of septal perforation. To grasp the timing of the same period of surgery, skilled endoscopic operation and postoperative dressing, can reduce the occurrence of septal perforation.