论文部分内容阅读
虽有些其它哺乳动物可存在真性多节指,但在人类极其少见。作者发现3例同胞患儿有这种类似情况。患儿的母亲在5次妊娠的每次妊娠期间,曾1天3次使用100mg苯妥英钠和15mg苯巴比妥治疗。有个婴儿是死胎,有个婴儿有小颅畸形和细指,出生8周后死亡。3个幸存下来的同胞患儿均有指甲发育不良,手指的末端遂渐变细、变长。第2例(男性)和第3例(女性)患儿比正常矮小,第1例(男性)出生体重低,有小颅畸形、腹股沟疝。第2例有室间隔缺损、右膈疝和髓质海绵肾。
Although some other mammals may have multiple testes, they are extremely rare in humans. The authors found that 3 cases of siblings with this similar situation. Children with mothers were treated with 100 mg phenytoin and 15 mg phenobarbital three times a day during each of five pregnancies. A baby is stillbirth, a baby has a small craniofacial deformity and thin fingers, died 8 weeks after birth. Three surviving siblings had nails dysplasia, the tip of the finger then tapered thin, longer. The second (male) and third (female) children were shorter than normal, and the first (male) was born with low birth weight, a small craniofacial deformity and an inguinal hernia. The second case of ventricular septal defect, right diaphragmatic hernia and medullary sponge kidney.