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通过观察不同治疗组的肾组织铅浓度和肾小管上皮细胞线粒体损伤数,研究碘化钾(KI)对大鼠实验性铅性肾病的治疗作用。结果显示KI在驱出肾组织铅及线粒体修复作用方面均较二疏基T-酸钠(DMSA)为佳,差异有高度显著性(P<0.01)。
To investigate the therapeutic effect of KI on experimental lead nephropathy in rats by observing the lead concentration in renal tissue and the number of mitochondrial damage in renal tubular epithelial cells of different treatment groups. The results showed that KI was better than DMSA in excreting lead and mitochondria in renal tissue, the difference was highly significant (P <0.01).