各种抗菌药物引起的腹泻已被重视。Jewkes等报道的71例成人急性腹泻中,抗生素引起的居第三位。此类腹泻轻重不同,轻者仅有稀便、便次增多;重者为假膜性结肠炎,可并发肠梗阻、中毒性巨结肠症等,甚至致死。若在临床上将此类腹泻误认为是一般肠道致病菌所引起,就会投用更多的抗菌药物,加重腹泻,导致不良后果。诊断抗菌药物引起腹泻的基本条件如下:①腹泻发生在应用抗菌药物时或停用四周之内;②每日排便在3次以上的不成形粪便,而不能用其它原因 Diarrhea caused by various antibiotics has been taken seriously. In 71 adult cases of acute diarrhea reported by Jewkes et al, antibiotics caused the third highest risk. Such diarrhea of ​​different severity, light only loose stools, then times increased; severe cases of pseudomembranous colitis, intestinal obstruction may be toxic, toxic Hector’s disease, and even death. If such diarrhea is mistakenly considered as a general intestinal pathogenic bacteria in clinical practice, more antibacterial drugs will be administered to aggravate diarrhea and lead to adverse consequences. The basic conditions for diagnosis of diarrhea diagnosed with antibiotics are as follows: ① diarrhea occurs within four weeks of the application of antibacterial drugs; ② daily defecation in more than three times the shape of feces, and can not be used for other reasons