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目的探讨埃索美拉唑联合莫沙比利治疗反流性食管炎(RE)的临床疗效。方法选取2008年至2010年新野卫生职业中专附属医院治疗的86例RE患者,将其随机分成两组:治疗组和对照组各43例,治疗组用埃索美拉唑+莫沙比利治疗,对照组采用奥美拉唑+多潘立酮治疗,4周后观察两组的临床症状改善率,并评价内镜下有效率。结果 4周后,治疗组临床总有效率为为93.02%,内镜下总有效率90.70%;对照组临床总有效率为72.09%,内镜下总有效率为69.77%;两组比较差异有统计学意义(P<0.05)。结论埃索美拉唑联合莫沙比利治疗RE效果良好,值得推广。
Objective To investigate the clinical efficacy of esomeprazole combined with mosapride in the treatment of reflux esophagitis (RE). Methods Eighty-eight RE patients treated by Xinye Health Vocational College Affiliated Hospital from 2008 to 2010 were randomly divided into two groups: the treatment group and the control group, 43 cases each. The patients in the treatment group were treated with esomeprazole + mosapride The patients in the control group were treated with omeprazole and domperidone. After 4 weeks, the improvement rate of clinical symptoms and the efficiency of endoscopy were evaluated. Results After 4 weeks, the total effective rate was 93.02% in the treatment group and 90.70% in the endoscopic group. The total effective rate was 72.09% in the control group and 69.77% in the endoscopic group. The difference between the two groups was Statistical significance (P <0.05). Conclusion Esomeprazole combined with mosapride in the treatment of RE is effective and worthy of promotion.