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本文报告30例健康人及110例原发性高血压患者血浆心房利钠因子(ANF)水平及其与高血压性心脏病、原发性高血压的肾素分型,疾病分期及巯甲丙脯酸治疗前后的关系。结果表明,健康人及患者组基础值均显著高于激发值;患者组基础值显著高于健康组;高心病组显著高于非高心病组;低肾素型组显著高于正常肾素型及高肾素型组;使用巯甲丙脯酸治疗后,血浆ANF水平显著低于治疗前;但与原发性高血压病情的严重程度则无明确的关系。原发性高血压血浆ANF水平的升高,主要与心、肺血容量的变化密切相关。
This article reports the plasma levels of atrial natriuretic factor (ANF) in 30 healthy subjects and 110 patients with essential hypertension and its correlation with hypertension heart disease, renin classification of essential hypertension, stage of disease, Pre-acid treatment before and after the relationship. The results showed that the basal value of healthy people and patients were significantly higher than the value of stimulation; the basic value of patients was significantly higher than that of healthy group; the incidence of hyperglycemia was significantly higher than that of non-cardial disease; And high-renin group. After treatment with captopril, plasma ANF level was significantly lower than before treatment; however, there was no clear relationship between the severity of essential hypertension and the severity of the disease. Essential hypertension plasma ANF levels, mainly with heart and lung volume changes are closely related.