乳腺癌是女性最常见的恶性肿瘤,多发于45~50岁,近年来其发病率和死亡率均有较快增长。双侧原发性乳腺癌是乳腺癌的特殊类型之一,一般认为其发生率占所有乳腺癌总数的1%~2%。随着早期乳腺癌的检出比例增加,单侧乳腺癌的术后随访时间不断延长,双侧原发性乳腺癌的比例也有所提高[1 Breast cancer is the most common malignant tumor in women, which occurs in 45 ~ 50 years old. In recent years, its morbidity and mortality have been increasing rapidly. Bilateral primary breast cancer is a special type of breast cancer, the incidence is generally believed that the incidence of all breast cancer, the total number of 1% to 2%. As the proportion of early breast cancer increases, postoperative follow-up of unilateral breast cancer continues to increase and the proportion of bilateral primary breast cancer also increases [1