目的探讨胸腔镜微创手术与传统开胸手术治疗纵隔肿瘤的临床疗效。方法 25例行胸腔镜微创手术治疗的纵隔肿瘤患者作为观察组,另选取同期25例行传统开胸手术治疗的纵隔肿瘤患者作为对照组,对比两组的临床疗效。结果在手术时间、术中出血量、引流时间、使用镇痛药时间、住院时间方面比较,观察组明显优于对照组,差异有统计学意义(P<0.05)。在住院费用方面比较差异无统计学意义(P>0.05)。结论胸腔镜微创手术治疗纵隔肿瘤的临床疗效显著,具有创伤小、恢复快等优点,值得临床推广应用。 Objective To investigate the clinical effects of thoracoscope minimally invasive surgery and conventional thoracotomy for the treatment of mediastinal tumors. Methods Twenty-five patients undergoing minimally invasive thoracoscopic surgery for mediastinal tumor were selected as the observation group. Twenty-five patients with mediastinal tumors treated by conventional thoracotomy during the same period were selected as the control group, and the clinical efficacy was compared between the two groups. Results Compared with the control group, the observation group was significantly better than the control group in the operation time, intraoperative blood loss, drainage time, the use of analgesic time, hospital stay, the difference was statistically significant (P <0.05). There was no significant difference in hospitalization costs (P> 0.05). Conclusions The minimally invasive thoracoscopic surgery for the treatment of mediastinal tumors has a significant clinical effect, has the advantages of less trauma and faster recovery, and is worthy of clinical application.