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目的探讨短暂性脑缺血发作(TIA)发作频率与临床特征的关系。方法从南京卒中注册数据库中选择符合研究方案的TIA患者172例,按照发作频率分为单发性TIA和多发性TIA(发作次数≥2),多发性TIA按照每次发作症状是否相同分为刻板性TIA和变异性TIA,对不同发作频率TIA的临床特征进行分析。结果单发性TIA和多发性TIA比较,房颤、肢体无力多见于单发性TIA(P＜0．05),颅内外大动脉病变多见于多发性TIA(P＜0．05)；刻板性TIA和变异性TIA比较,颅内外大动脉病变多见于刻板性TIA(P＜0．05)。结论颅内外大动脉病变常见于多发性TIA和刻板性TIA,房颤、肢休无力多见于单发性TIA。对TIA患者应根据发作频率和症状不同进行相应的病因检查。
Objective To investigate the relationship between the frequency of seizures and clinical features in patients with transient ischemic attack (TIA). Methods 172 cases of TIA patients were selected from Nanjing Stroke Registration Database and divided into single TIA and multiple TIA according to seizure frequency (number of seizure≥2). Multiple TIA was divided into three groups according to whether the symptoms were the same Sexual TIA and Variant TIA, the clinical features of different seizure frequency TIA were analyzed. Results Compared with multiple TIA, AF and AFV were more common in single TIA (P <0.05), and extracranial and extracranial arterial lesions were more common in multiple TIA (P <0.05). Stereotyped TIA Compared with the variability of TIA, intracranial extra-arterial lesions were more common in stereotypical TIA (P <0.05). Conclusions Extracranial and extracranial arterial lesions are common in multiple TIA and rigid TIA. Atrial fibrillation and limb weakness are common in single TIA. TIA patients should be based on the frequency of attacks and symptoms of the corresponding etiological examination.