患儿女,10天,因“纳差5天”入院。患儿系第1胎第1产,胎龄39周剖宫产,出生体重3400 g,无窒息史,否认遗传病家族史。生后母乳喂养,生后5天患儿出现吃奶差,予“酪酸梭菌二联活菌、维生素C”口服后无明显好转来我院就诊。查体:反应一般,面色苍白,皮肤弹性差,哭闹时皮肤可见花纹样改变,心肺腹部无异常,四肢肌张力高,下肢交叉步, Children with children, 10 days, due to “anorexia 5 days ” admission. Children with first birth of the first fetus, 39 weeks gestational age cesarean section, birth weight 3400 g, no history of asphyxia, deny family history of genetic disease. After birth, breastfeeding, 5 days after birth in children with poor feeding, to “Clostridium butyricum viable, vitamin C,” no obvious improvement after oral administration to our hospital. Physical examination: general reaction, pale, poor skin elasticity, pattern changes seen in the skin when crying, no abnormal heart and lung abdomen, limb muscle tension, lower limb cross step,