疣样癌(verrucous carcinoma)是上皮癌的一种类型,Ackerman(1948)最早加以描述。疣样癌的病因与局部慢性刺激有关,如吸烟、鼻烟、咀嚼槟榔子等。肿物具有凸出增生的特性,与多种上皮癌相似,常发生于颊粘膜,可侵及口腔任何部位。也可发生于喉部。偶见生殖器及鼻腔疣样癌。此病常见于老年男性患者,但也有发生于年青人及女性者。在吸鼻烟比较普及的地区尤为常见.疣样癌的病理切片表现为上皮增厚,上皮表面有成熟的正常细胞,不向邻近组织浸润,无角比不全,基底膜完整,因此有时误诊为良性角质增生症。上皮角化物形成柱状,像“打桩”那样插入上皮及基底膜,其进入深部组 Verrucous carcinoma is a type of epithelial carcinoma that was first described by Ackerman (1948). The cause of melanoid cancer is related to local chronic irritation, such as smoking, snuff, and chewing betel nuts. Tumors have the characteristic of protruding hyperplasia, similar to a variety of epithelial cancers, and often occur in the buccal mucosa and can invade any part of the oral cavity. It can also occur in the throat. Occasional genital and nasal carcinoid cancer. The disease is common in older men, but it also occurs in young people and women. It is especially common in areas where snuff is more common. The pathological section of the carcinoid tumor is characterized by epithelial thickening, mature normal cells on the surface of the epithelium, no infiltration into neighboring tissues, no angular insufficiency, and complete basement membrane, which is sometimes misdiagnosed as benign. Hyperkeratosis. The epithelial keratin is formed into a columnar shape and inserted into the epithelium and basement membrane as “piling” into the deep group.