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目的了解南宁地区腹泻婴幼儿A群轮状病毒感染情况及流行特征。方法对2011年1月-2014年12月在本院就诊的17 695例腹泻婴幼儿的粪便,采用免疫层析法检测轮状病毒抗原并收集临床诊断信息,分析轮状病毒流行特征。结果 17 695例婴幼儿中A群轮状病毒感染率为18.04%,不同性别患儿间感染率差异无统计学意义(P>0.05)。10.98%的感染患儿伴有呼吸系统疾病、呕吐、脱水及神经系统症状。全年均有感染发生,12月均为高峰;1岁~2岁患儿感染率最高,为28.63%,其次为6个月~1岁组和2岁~3岁组,感染率分别为20.64%和17.69%,各年龄组婴幼儿间感染率比较差异有统计学意义(P<0.05)。结论南宁地区腹泻婴幼儿轮状病毒感染率较高,好发于冬季,6个月~3岁婴幼儿为易感人群。
Objective To understand the prevalence and epidemiological characteristics of rotavirus A in infants and infants in Nanning. Methods A total of 17 695 cases of diarrhea infants in our hospital from January 2011 to December 2014 were enrolled in this study. The rotavirus antigen was detected by immunochromatography and the clinical diagnostic information was collected to analyze the epidemiological characteristics of rotavirus. Results Among 17 695 infants and young children, the infection rate of group A rotavirus was 18.04%. There was no significant difference in the infection rates among children with different sex (P> 0.05). 10.98% of infected children were accompanied by respiratory diseases, vomiting, dehydration and nervous system symptoms. Infection occurred in all the year and peaked in December. The highest infection rate in children aged 1 to 2 years was 28.63%, followed by 6 months to 1 year group and 2 to 3 years old group, the infection rates were 20.64 % And 17.69% respectively. There was significant difference in the infection rate between infants and young children in all age groups (P <0.05). Conclusions The incidence of rotavirus infection in infants and young children in Nanning is high. It occurs predominantly in winter, and infants from 6 months to 3 years old are susceptible.