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目的探讨破血抗孕方结合甲氨蝶呤子宫动脉灌注栓塞术治疗输卵管妊娠的临床疗效。方法 60例患者随机分为两组,治疗组采用经导管灌注甲氨蝶呤100 mg后再用明胶海绵颗粒栓塞子宫动脉,术后口服破血抗孕方一周;对照组采用经导管灌注甲氨蝶呤100 mg后再用明胶海绵颗粒栓塞子宫动脉,术后一周开始观察临床体征、监测血清人绒毛膜促性腺激素值、B超监测孕囊变化情况。结果 56例获得成功,成功率达93.33%,无严重不良反应,术血β-HCG值下降至正常所需时间10~20天,包块消失时间约14~40天。结论子宫动脉灌注栓塞术协同破血抗孕方治疗输卵管妊娠,可有效降低HCG水平,促进异位妊娠包块的软化、吸收及消散,其疗效高且副反应小,最大限度的恢复患者的生殖功能。
Objective To investigate the clinical efficacy of “Xuexue Kangsheng Fang” combined with methotrexate uterine arterial infusion embolization in the treatment of tubal pregnancy. Methods Sixty patients were randomly divided into two groups. The patients in the treatment group were treated with 100 mg methotrexate via catheter and then embolized uterine artery with gelatin sponge particles. One month after operation, Pterygium 100 mg gelatin sponge particles embolization of uterine artery, one week after surgery to observe the clinical signs, monitoring of serum human chorionic gonadotropin value, B ultrasound monitoring changes in gestational sac. Results 56 cases were successful, the success rate was 93.33%, no serious adverse reactions, blood β-HCG decreased to normal time 10 to 20 days, mass disappearance of about 14 to 40 days. Conclusion Uterine arterial perfusion and embolization combined with blood-letting and anti-pregnancy treatment of tubal pregnancy can effectively reduce the level of HCG and promote the softening, absorption and dissipation of ectopic pregnancy mass. The curative effect is high and the side reaction is small, so as to maximize the reproduction of patients Features.