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患者男,26岁,既往健康。因上腹部饱胀于15小时内口服胃复安总量120mg(江苏宜兴市制药厂生产)。2小时后出现颈项强直后仰,张口困难,四肢震颤,静坐不能等锥体外系症状,同时伴有心悸、胸闷症状,于1993年2月15日上午10时入院。查体:T36.8℃,P107次/分,R19次/分,BP16/10KPa,神志清,无发绀,恐惧面容,颈项强直后仰,活动受限,巩膜无黄染,两侧眼球有水平震颤,两肺部(—),心率107次/分,律齐,各瓣膜区未闻及杂音,腹软,肝脾不肿大。神经系统检查:四肢肌张力增强,有震颤,克氏征,巴氏征均(—)。化验血尿粪常规均无异常。胸部X线透视,心、肺、膈均(—)。心电图:窦性心动过速,心率107次/分,T波Ⅱ、aVFⅦ、V_4—V_6低平,双
Male patient, 26 years old, past health. Due to the fullness of the upper abdomen within 15 hours of oral administration of metoclopramide total 120mg (Jiangsu Yixing Pharmaceutical Factory production). 2 hours after the emergence of neck stiffness backwards, mouth opening difficulties, extremities tremors, can not wait outside the extrapyramidal symptoms, accompanied by palpitations, chest tightness symptoms, at 15 o’clock on the February 15, 1993 admission. Physical examination: T36.8 ℃, P107 beats / min, R19 beats / min, BP16 / 10KPa, clear mind, no cyanosis, fear face, neck stiffness backwards, limited activity, scleral no yellow dye, eye level on both sides Tremor, both lungs (-), heart rate 107 beats / min, law Qi, the valve area did not smell and noise, belly soft, liver and spleen not swollen. Neurological examination: limb muscle tone increased, tremor, Kirschner sign, Pakistan sign (-). Laboratory blood and urine were normal no abnormalities. Chest X-ray, heart, lung, diaphragm are (-). ECG: sinus tachycardia, heart rate 107 beats / min, T wave Ⅱ, aVF Ⅶ, V_4-V_6 low flat, double