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三、常用钙拮抗剂 1.硫氮(艹卓)酮扩张外周血管,解除冠状动脉痉挛,延长房室结不应期,轻度抑制心肌收缩力。常用于冠心病心绞痛,对由冠脉痉挛所致的变异性心绞痛疗效更佳。亦可用于阵发性室上性心动过速或某些难治性血管痉挛所致的偏头痛。用法及注意事项:每次30～60mg,每日3～4次,口服后30min起效。半衰期为3～9h,可有心动过缓、房室传导阻滞、低血压及恶心,呕吐等副作用。心肾功能不全者慎用。 2.心痛定为钙通道阻滞剂,抑制血管平滑肌钙内流,直接扩张冠状动脉及外周血管,防止冠
Third, commonly used calcium antagonist 1. Sulfur Nitrogen (艹 Zhuo) ketone expansion of peripheral blood vessels to relieve coronary artery spasm, prolong the atrioventricular node refractory period, mild inhibition of myocardial contractility. Commonly used in patients with coronary heart disease angina pectoris, caused by coronary spasm variability angina better. Can also be used for paroxysmal supraventricular tachycardia or some refractory vasospasm caused by migraine. Usage and precautions: Each 30 ~ 60mg, 3 to 4 times daily, 30min after oral effect. Half-life of 3 ~ 9h, may have bradycardia, atrioventricular block, hypotension and nausea, vomiting and other side effects. Heart and kidney dysfunction with caution. 2. Heartache as a calcium channel blocker, inhibition of vascular smooth muscle calcium influx, direct expansion of coronary arteries and peripheral vessels, to prevent the crown