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对21名男性原发性高血压患者进行了红细胞~(86)R_b摄取率测定。与22名男性正常血压者相比,患者的哇巴因敏感~(86)摄取率降低R_b提示男性原发性高血压患者的红细胞钠泵活性降低。患者组的哇巴因敏感~(86)R_b摄取率与血压负相关;而正常血压组这一组分的摄取率与血压不相关,但与年龄负相关。二组间其它摄取组分均无差别。本文还对原发性高血压患者红细胞钠泵活性低下的意义和原因作了讨论。
Erythrocyte ~ (86) R_b uptake was measured in 21 male patients with essential hypertension. Compared with 22 men with normotensive blood pressure, the decreased ouabain-induced (86) uptake rate in patients with Rb suggests a decrease in erythrocyte sodium pump activity in men with essential hypertension. The uptake rate of ouabain-sensitive (86) R_b in patients was negatively correlated with blood pressure, while the uptake of this component in normotensives was not related to blood pressure but negatively correlated with age. There was no difference in other uptake components between the two groups. This article also discusses the significance and causes of low erythrocyte sodium pump activity in patients with essential hypertension.