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通过多设施的公开试验作者对丙丁酚(probucol)治疗睑黄瘤进行了研究,结果发现不管血清胆固醇值高低,均有使睑黄瘤明显减退的疗效。将不论有无高胆固醇血症、但能判断疗效的50例睑黄瘤患者分为220mg/dl以上的高胆固醇血症组和220mg/d l以下的正常组,每组各25例。每日1000mg丙丁酚于早、晚进餐后分别两次给药,给药时间为6个月～2年。经肉眼观察和彩色照片判断一致,发现高胆固醇血症组23例(92%)、正常组17例(68%)黄瘤减退。其中消退者5例。两组投给丙丁酚1个月后
Through a multi-facility open-trial study of probucol for the treatment of eyelid xanthomas, it was found that there was a significant ef? Cacy reduction in eyelid xanthomas regardless of serum cholesterol levels. Fifty cases of paloma treated with or without hypercholesterolemia were divided into hypercholesterolemia group of 220mg / dl or more and normal group of 220mg / dl or less, with 25 cases in each group. Daily 1000mg probucol morning and evening meals were administered twice a day for 6 months to 2 years. The naked eye observation and color photographs were consistent, found hypercholesterolemia group of 23 patients (92%), normal group of 17 cases (68%) decreased xanthoma. Which subsided in 5 cases. Two groups were given probucol one month later