论文部分内容阅读
目的检测正常及白内障猕猴眼的组织结构,以供进一步的研究。方法40只猕猴眼(14只白内障)行裂隙灯、检眼镜、眼压检查,测量角膜的大小和房水量及细胞计数。摘除的眼球分别作火棉胶和石蜡包埋,光学显微镜下观察。结果猕猴眼球的前后径为(21. 0±0. 72)mm、水平径(20. 2±0. 69)mm、垂直径(19. 6±0. 71)mm。其角膜大小及眼压基本同人类。房水量平均为(180±0.028)μl,房水中无细胞。正常猕猴眼内组织结构与人眼有些差异。猕猴白内障的形态和病理改变同人眼。结论作为高等动物,尤其进行临床前的实验研究,猕猴是最理想的动物模型。
Objective To detect the structure of normal and cataract eyes in Macaca mulatta for further study. Methods Forty kiwi eyes (14 cataracts) underwent slit lamp, ophthalmoscopy and intraocular pressure examinations. The corneal size, aqueous humor volume and cell count were measured. Excised eyeballs were made of collodion and paraffin embedded, observed under light microscope. Results The anterior and posterior diameters of the eyes of the cynomolgus monkey were (21. 0 ± 0.72) mm, horizontal diameter (20.2 ± 0.69) mm, vertical diameter (19.6 ± 0.71) mm. The corneal size and intraocular pressure basically the same human. The average amount of aqueous humor (180 ± 0.028) μ, no aqueous cells. There are some differences between normal eye tissue and human eye. Macaque cataract morphology and pathological changes with the human eye. Conclusion As a higher animal, especially pre-clinical experimental study, macaque is the most ideal animal model.