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目的探讨神经梅毒的临床及磁共振成像特点。方法对本院收治的7例神经梅毒患者的临床资料、实验室检查、磁共振成像结果进行回顾性分析。结果临床常以间质型梅毒,尤其以脑膜血管梅毒常见,临床表现缺乏特异性;血清学检查以梅毒螺旋血凝集试验特异性较高,而脑脊液梅毒诊断实验阳性率低于血清;头部MRI以梅毒树胶肿表现典型。结论神经梅毒早期误诊率高,临床表现多样,应结合实验室及磁共振成像检查综合分析。
Objective To investigate the clinical and MRI features of neurosyphilis. Methods The clinical data, laboratory tests and MRI findings of 7 cases of neurosyphilis admitted in our hospital were analyzed retrospectively. Results Often, interstitial syphilis was used clinically, especially in patients with meningeal vascular syphilis. The specificity of serology was high in patients with syphilis and the positive rate of CSF syphilis was lower than that in serum MRI with typical symptoms of syphilis gum. Conclusion The early diagnosis of neurosyphilis misdiagnosis rate, clinical manifestations should be combined with laboratory and magnetic resonance imaging examination comprehensive analysis.