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目的:了解我院喹诺酮类药致不良反应发生特点与一般规律。方法:对2007～2008年我院ADR监测中心收集到的187例喹诺酮类药致ADR报表进行汇总分析。结果:187例ADR报表中涉及6种喹诺酮类药,最常见的不良反应是皮肤及其附件损害和消化系统反应,多数不良反应的转归情况良好,注射剂容易引起ADR,发生ADR的喹诺酮类药以加替沙星最多。结论:喹诺酮类药发生ADR与多种因素相关,临床使用时应高度重视喹诺酮类药不良反应的监测,减少ADR的发生。
Objective: To understand the characteristics and general rules of quinolone-induced adverse reactions in our hospital. Methods: A total of 187 quinolones-induced ADRs collected from ADR surveillance center of our hospital from 2007 to 2008 were collected and analyzed. Results: Of the 187 ADRs, 6 quinolones were involved. The most common adverse reactions were damage to the skin and its accessory organs and digestive system reactions. The majority of ADRs were in good condition. Injections were prone to cause ADR and quinolones with ADR Gatifloxacin up to. Conclusion: The occurrence of quinolone is related to many factors. In clinical use, the monitoring of adverse reactions of quinolones should be paid great attention to reduce the occurrence of ADR.