脑膜炎球菌感染发生症状后,患者可在数小时内死亡,年龄在2岁以下的儿童,其死亡率特别高。作者详细调查了10例(年龄为1周至2岁)因脑膜炎球菌感染而死亡的儿童病例。所有病例在出现出血性皮疹平均13小时前都有行为改变的前驱症状。其它常见症状为:烦燥(9例)、发热(8例)、不食(7例)、叫喊(6例)、昏睡(6例)和脸色苍白(3例)。面部与驱干出现弥散性、淡粉红色斑疹性前驱皮疹。1例在吃了一点东西后5小时死于家中,仅发现皮疹。死于医院中的9例儿童中,7例在入院时都有典型的出血性皮疹。出血性皮疹、血管内凝血是最常见的体 After the onset of symptoms of meningococcal disease, the patient can die within hours and children under 2 years of age have a particularly high mortality rate. The authors investigated in detail 10 children (1 week to 2 years old) who died of a meningococcal infection. All cases had a precursor to behavioral change before an average of 13 hours of hemorrhagic rash occurred. Other common symptoms were irritability (n = 9), fever (n = 8), nausea (n = 6), lethargy (n = 6) and paleness (n = 3). Diffuse facial and dry diffuse, pale pink rash precursor rash. One patient died at home 5 hours after eating a little and found only a rash. Of the 9 children who died in the hospital, seven had a typical hemorrhagic rash on admission. Hemorrhagic rash, intravascular coagulation is the most common body