发病情况1885年,Paltauf首次报告全身播散型毛霉菌病,尸检发现脑组织受侵。1943年,Gregory报告由鼻腔、眼眶侵入颅内的毛霉菌病。人类毛霉菌病有只侵犯皮肤者,多不致死,称为良性型。另有侵犯消化道、全身播散及鼻、眶、脑等处者,死亡率很高,称为恶性型。鼻脑型毛霉菌病近来有增多趋势。据DeWeese(1965)统计约占毛霉菌病的 Morbidity In 1885, Paltauf reported for the first time a system of disseminated mucormycosis, which revealed an invasion of brain tissue at necropsy. In 1943, Gregory reported intracranial mucormycosis in the nose and eyes. Human mucormycosis has only violations of the skin, do not lethal, known as benign. Another violations of the digestive tract, systemic dissemination and nose, orbit, brain and other places, the high mortality rate, known as the malignant type. Nasopharyngeal mucormycosis has an increasing trend recently. According to DeWeese (1965) statistics about the proportion of moldy