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目的分析大庆地区孕前及孕早期妇女风疹与巨细胞病毒的感染状况,为孕前门诊、遗传和优生咨询门诊指导优生,降低先天畸形儿出生率提供理论依据。方法对5700例孕前及孕早期女性开展风疹病毒lgG和IgM,巨病毒IgG和IgM抗体检测,分析孕前和孕早期女性巨细胞病毒与风疹病毒的感染率。结果巨细胞病毒不同年龄段间易感率差异无统计学意义(P>0.05),而不同年龄段对象风疹的易感率差异有统计学意义(P<0.01),年龄在35岁~39岁易感率最高,为13.66%。结论应加强对高危年龄段孕妇的筛查。对于筛查结果IgM为阳性的孕妇应采取羊水、脐血或绒毛组织进行胎儿宫内感染的产前诊断。
Objective To analyze the prevalence of rubella and cytomegalovirus infection among pregnant women and pregnant women in Daqing region in order to provide theoretical basis for prenatal care, genetic counseling and prenatal counseling for eugenics and to reduce the birth rate of congenital malformations. Methods The detection of rubella virus lgG and IgM, giant virus IgG and IgM antibodies in 5700 pregnant women before and after pregnancy was carried out. The infection rates of female cytomegalovirus and rubella virus before and after pregnancy were analyzed. Results There was no significant difference in the susceptibility of cytomegalovirus among different age groups (P> 0.05), while the susceptibility to rubella in different age groups was significantly different (P <0.01), and the age ranged from 35 to 39 years The highest susceptibility was 13.66%. Conclusions Screening of pregnant women in high-risk age groups should be strengthened. For screening results IgM positive pregnant women should take amniotic fluid, cord blood or chorionic tissue for prenatal diagnosis of intrauterine infection.