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目的:研究急性CO中毒患者血清内NSE(神经元特异性烯醇化酶)及SOD(超氧化物歧化酶)水平与中毒严重程度。方法:选取不同程度CO中毒患者93例,分轻度、中度、重度中毒各31例,在中毒后6h内及治疗后分别测定其血清内的NSE值和SOD值,选取健康体检30例患者测定其血清内的NSE值及SOD值。结果:中毒组的NSE及SOD值的较对照组有明显改变,差异有统计学意义,轻度中毒组较对照组、中毒中毒组较轻度中毒组差异有统计学意义,而重度中毒组较中度中毒组差异无统一学意义。结论:NSE和SOD有助于判断急性CO中毒的严重程度,具有积极的临床意义。
Objective: To study the levels of NSE (neuron-specific enolase) and SOD (superoxide dismutase) and the severity of poisoning in patients with acute CO poisoning. Methods: Ninety-three patients with mild or moderate and severe poisoning were selected from different degrees of CO poisoning. NSE and SOD in serum were determined within 6h after poisoning and after treatment, and 30 healthy subjects were selected Determination of serum NSE value and SOD value. Results: Compared with the control group, the NSE and SOD of the poisoning group were significantly changed, the difference was statistically significant, the mild poisoning group than the control group, the poisoning poisoning group had a statistically significant difference compared with the mild poisoning group, while the severe poisoning group There is no uniform significance in the moderate poisoning group. Conclusion: NSE and SOD can help determine the severity of acute CO poisoning, with a positive clinical significance.