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The current method of estimating the fatigue life of railway structures is to calculating the equivalent stress amplitude based on the measured stress data.However,the random of the measured data is not considered.In this paper,a new method was established to compute the equivalent stress amplitude to evaluate the fatigue damage based on the measurable randomness,since the equivalent stress is the key parameter for assessment of structure fatigue life and load derivation.The equivalent stress amplitude of a high-speed train welded bogie frame wasfound to obey normal distribution under uniform operation route that verified by on-track dynamic stress data,and the proposed model is,in effect,an improved version of the mathematical model used to calculate the equivalent stress amplitude.The data of a long-term,on-track dynamic stress test program was analyzed to find that the normal distribution parameters of equivalent stress amplitude values differ across different operation route.Thus,the fatigue damage of the high-speed train welded bogie frame can be evaluated by the proposed method if the running schedule of the train is known a priori.The results also showed that the equivalent stress amplitude of the region connected to the power system is more random than in other regions of the bogie frame.