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我院在1989～1993年间,用南京大学制药厂生产的尿激酶治疗老年人急性心肌梗塞(AMI)33例小结如下: 临床资料一、一般资料 33例中男21例,女12例。年龄在61～75岁(平均64.4岁)。发病到开始用药时间:90～360min,平均320.7min。梗塞部位:下壁10例、下壁加正后壁8例、前壁4例,广泛性前壁11例。伴心力衰竭15例(占45.5％),心源性休克9例(占27.2％)。二、治疗方法本组采用尿激酶100～160万u加生理盐水100ml,静滴,30～40min滴完。于滴完后6h若ACT<150sec,给肝素钙7500u,腹壁皮下注射,12h,连用5～7d。同时给阿斯匹林0.3g,qd,3天后改50mg,qd及血管扩张剂、抗心律失常等对症处理。
Our hospital in 1989 to 1993, with Nanjing University Pharmaceutical Factory production of urokinase in elderly patients with acute myocardial infarction (AMI) 33 are summarized as follows: Clinical data First, the general information 33 cases of male 21 cases, 12 females. The age of 61 to 75 years (average 64.4 years old). The onset of medication time: 90 ~ 360min, an average of 320.7min. Infarct sites: 10 cases of inferior wall, 8 cases of posterior wall plus posterior wall, 4 cases of anterior wall, and 11 cases of extensive anterior wall. There were 15 cases (45.5%) with heart failure and 9 cases (27.2%) with cardiogenic shock. Second, the treatment of this group of urokinase 100 ~ 160 million u plus saline 100ml, intravenous drip, 30 ~ 40min drip finished. 6 hours after the drop if ACT <150sec, to heparin calcium 7500u, abdominal wall subcutaneous injection, 12h, once every 5 ~ 7d. At the same time to aspirin 0.3g, qd, 3 days to change 50mg, qd and vasodilators, anti-arrhythmia and other symptomatic treatment.