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目的探讨原发性肝脏平滑肌肉瘤(primary hepatic leiomyosarcoma,PHLMS)的病理学及免疫组织化学表现。方法应用组织病理学、免疫组织化学方法观察3例原发性肝脏平滑肌肉瘤。结果组织学观察瘤细胞呈梭形,可见核分裂;免疫组织化学结果Smooth Muscle Actin(+)、CD117(-)、S-100(-)、Vimentin(-)。结论原发性肝脏平滑肌肉瘤是一种罕见的恶性间叶肿瘤,其诊断主要依靠免疫组织化学方法。
Objective To investigate the pathological and immunohistochemical findings of primary hepatic leiomyosarcoma (PHLMS). Methods Histopathological and immunohistochemical methods were used to observe 3 cases of primary hepatic leiomyosarcoma. Results Histological observation showed that the tumor cells were fusiform and showed mitosis. The results of immunohistochemistry were as follows: Smooth Muscle Actin (+), CD117 (-), S-100 (-) and Vimentin (-). Conclusion Primary liver leiomyosarcoma is a rare malignant mesenchymal tumor whose diagnosis mainly depends on immunohistochemistry.