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X综合征患者有心绞痛,但在冠脉造影时并无冠脉粥样硬化或痉挛的依据,其冠脉微血管扩张能力不足,当心肌耗氧量增加则出现心肌缺血.作者比较了异搏停和心得安治疗该病的疗效。方法:28例心绞痛病人,冠脉造影正常,16例具备下列条件作为受试对象.①缺血型ST段降低≥0.15mv,持续时间>1分.②运动试验诱发典型心绞痛和缺血型ST段降低.③麦角硷试验阴性(总剂量0.65mg.iv).平均年龄47.4±6岁.双盲试验前停用所有药物,必要时可口含硝酸甘油,决定每个病人心得安用量,服药后休息时心率≤60/分.2天试行期后随机让病人服心得安或异搏
Patients with Syndrome X have angina pectoris but have no evidence of coronary atherosclerosis or spasticity at coronary angiography with inadequate coronary microvascular dilatation and myocardial ischemia when myocardial oxygen consumption is increased. Stop and feel safe treatment of the disease effect. Methods: Coronary angiography was normal in 28 patients with angina pectoris, and 16 patients had the following conditions as the subjects: ① The ischemic ST segment was reduced ≥0.15mv for duration> 1 minute.②The exercise test induced typical angina pectoris and ischemic ST Segment decreased.③Glygoline test negative (total dose 0.65mg.iv) .The average age of 47.4 ± 6 years old.All drugs were stopped before the double-blind trial, if necessary, deliciously containing nitroglycerin, decoction of each patient safe dosage, after taking the drug Resting heart rate ≤ 60 / min .2 days after the trial period of random patient comfort or flee