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目的探讨HPV、TCT联合阴道镜检查在早期宫颈病变筛查中的意义。方法将河池市第一人民医院2013年8月-2016年4月通过多种方式筛查明确诊断的早期宫颈病变患者153例作为研究对象,均通过HPV、TCT以及阴道镜单一性检测以及联合诊断,评估分析不同检测方式对早期宫颈病变筛查的准确率。结果通过TCT检测技术诊断发现TCT检测阳性(+)率达到37.25%(57/153),其中良性病变患者检出33例;通过HPV检测技术诊断HPV检测阳性(+)率为79.74%(122/153),其中良性病变患者检出94例;在病理学检查中明确诊断癌前病变患者到达33例,其中TCT诊断准确率为72.73%(24/33),HPV诊断准确率为84.85%(28/33),HPV、TCT联合阴道镜诊断准确率为100.00%(33/33),与单一性检测方式相对比差异有统计学意义(P<0.01)。结论 HPV、TCT联合阴道镜检查在早期宫颈病变筛查中检出率极高,增加诊断敏感性,避免误诊或漏诊,为患者后期病情阻断治疗、预防宫颈癌等意义重大,值得推广应用。
Objective To investigate the significance of HPV and TCT combined with colposcopy in the screening of early cervical lesions. Methods 153 cases of early diagnosed patients with early cervical lesions were screened by Hepatology First People’s Hospital from August 2013 to April 2016 by various methods. All of them were tested by HPV, TCT, colposcopy monotherapy and combined diagnosis , Evaluate and analyze the accuracy of different detection methods for early cervical lesions screening. Results The positive (+) rate of TCT detection was 37.25% (57/153) by TCT test and 33 cases were detected by benign disease. The positive rate of HPV testing by HPV test was 79.74% (122 / 153), of which 94 were detected in patients with benign lesions; 33 patients were diagnosed as precancerous lesions by pathological examination. The diagnostic accuracy of TCT was 72.73% (24/33), and the diagnostic accuracy of HPV was 84.85% (28 / 33). The diagnostic accuracy of HPV and TCT combined colposcopy was 100.00% (33/33), which was significantly different from that of monophasic test (P <0.01). Conclusion HPV and TCT combined with colposcopy in the detection of early cervical lesions detection rate is extremely high, increase the diagnostic sensitivity, to avoid misdiagnosis or missed diagnosis, treatment of patients with late disease prevention, prevention of cervical cancer is of great significance, it is worth to promote the application.