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本文就格列奈类药物的作用机制及临床应用作一综述。1格列奈类药物作用机制1·1恢复胰岛素分泌的第一时相,改善胰岛素抵抗Tankova等通过研究发现,瑞格列奈治疗2型糖尿病患者静脉葡萄糖耐量试验下胰岛素分泌的第一时相的幅度和胰岛素浓度时间曲线下面积明显增加〔1〕,Jyoti等通
This article reviews the mechanism of Gliclazide and its clinical application. 1 glinazones drug mechanism of action 1.1 to restore the first phase of insulin secretion and improve insulin resistance Tankova et al found that repaglinide treatment of type 2 diabetic patients with intravenous glucose tolerance test the first phase of insulin secretion Amplitude and insulin concentration time curve under the area significantly increased 〔1〕, Jyoti et al