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目的：探讨腹腔镜胆囊切除术治疗急性胆囊炎患者临床效果及感染预防措施。方法随机选取本院2010年1月-2013年9月间的50例急性胆囊炎患者，并随机分为对照组和研究组两组，对照组实施传统开腹手术，研究组实施腹腔镜胆囊切除术，对比两组患者手术出血量、手术时间和疼痛评分，并观察感染发生率。结果研究组23例手术成功，有2例需要中转开腹手术。研究组患者手术出血量、手术时间和疼痛评分明显优于对照组，差异有统计学意义（P＜0.05）；两组患者术后均出现感染，差异无统计学意义（P＞0.05）。结论腹腔镜胆囊切除术治疗急性胆囊炎患者效果良好，但需要充分考虑患者病情，选择合适的手术时机，同时还要加强术中术后操作，减少感染。“,”objective: to study the clinical effect of laparoscopic cholecystectomy for acute cholecystitis patients and infection prevention measures. Methods:randomly selected in our hospital between January 2010 - September 2010 the 50 cases of patients with acute cholecystitis, and randomly divided into control group and the team in the two groups, control group to implement the traditional open operation, the team implement laparoscopic cholecystectomy, compared two groups of patients with blood loss, operating time and pain scores, and observe the incidence of infection. Results: 23 cases of successful operation team, there are 2 cases need transfer laparotomy. The team surgery in patients with blood loss, operating time and pain score was better than control group, the difference was statisticaly significant (P 0.05). Conclusion: the treatment of patients with acute cholecystitis laparoscopic cholecystectomy effect is good, but need to give ful consideration to the patients, choosing appropriate surgical opportunity, but also strengthen the intraoperative, postoperative reduce infection.