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目的探讨影响广西围产儿先天性脑积水发生的影响因素,为制定相应的防控措施提供参考依据。方法对广西7个市的229例先天性脑积水围产儿的父母和229例正常围产儿的父母进行问卷调查,对可能影响围产儿先天性脑积水发生的因素进行单因素及多因素分析。结果多因素logistic回归分析结果显示,父亲年龄、母亲孕早期患病、母亲孕前或孕期有过物理或化学伤害、在母亲怀孕前半年或孕早期进行房屋装修是广西围产儿先天性脑积水的危险因素,而父亲的教育程度、母亲孕早期接受过优生检测、母亲服用叶酸是保护因素(P<0.05)。结论加强保护因素,减少和控制孕妇孕期的危险因素是预防围产儿先天性脑积水的重要手段。
Objective To investigate the influencing factors of congenital hydrocephalus in Guangxi perinatal infants and to provide reference for making corresponding prevention and control measures. Methods A total of 229 parents of congenital peritoneal hydrops in 229 cities of Guangxi and 229 parents of normal perinatal children were surveyed by questionnaire. Univariate and multivariate analyzes were conducted on the factors that may influence the occurrence of congenital hydrocephalus in perinatals. . Results Multivariate logistic regression analysis showed that the age of the father, the disease of the mother during the first trimester, the physical or chemical damage of the mother before or during pregnancy, and the congenital hydrocephalus of the perinatal infants in Guangxi during the first six months of pregnancy or the first trimester of pregnancy Risk factors, while the level of education of the father, the mother received early detection of euthymes, mothers take folic acid is a protective factor (P <0.05). Conclusion To strengthen the protective factors and reduce and control the risk factors of pregnant women during pregnancy is an important means to prevent congenital hydrocephalus in perinatal children.