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动脉粥样硬化在肥胖者中发病率明显增高。肥胖者与消瘦者相比,冠状动脉粥样硬化性心脏病的发生率为5:1。有人曾对30—40岁人群作长达14年的随访,发现肥胖者血脂增高是形成动脉粥样硬化的重要原因。血脂增高者易于发生冠心病,并且随着胆固醇值的升高,病死率也增高。高血压、糖尿病及吸烟等因素也使肥胖者患动脉粥样硬化的危险性增加,并促进低密度脂蛋白进入动脉壁,沉积在内膜,使动脉壁增厚,管腔变窄。
Atherosclerosis in the incidence of obesity was significantly higher. The incidence of coronary atherosclerotic heart disease was 5: 1 in obese subjects compared with those in wastesters. Some people have 30-40 years of age for up to 14 years of follow-up, found that obesity increased blood lipids is an important cause of atherosclerosis. High blood lipids are prone to coronary heart disease, and with the increase of cholesterol, fatality rates also increased. Hypertension, diabetes and smoking and other factors also increase the risk of atherosclerosis in obese people and promote low-density lipoprotein into the arterial wall, deposited in the intima, the arterial wall thickening, lumen narrowing.