远端型脊肌萎缩症一家系二例刘斌臧贺川唐启攵群例１（先证者），男，２８岁。因８年前无诱因出现双下肢无力，腿逐渐变细，３年前出现双上肢无力，近１年抬腿困难，跛行就诊。无尿、便障碍。父母非近亲婚配。查体：发育正常。颅神经正常。双上肢近端肌力Ⅳ级，远端肌力Ⅲ... Distal type of spinal muscular atrophy in two cases of a family Liu Bin Zang Hechuan Tang Kai group 1 (proband), male, 28 years old. 8 years ago, there is no incentive for both lower extremity weakness, legs tapering, upper extremity weakness appeared three years ago, leg raising difficulties in nearly a year, limping treatment. Anuria, it will be obstacles. Parents non-relatives marriage. Physical examination: normal development. Cranial nerve normal. Upper limb proximal muscle strength class Ⅳ, distal muscle strength Ⅲ