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目的:观察激素芬吗通+中药调经汤对肾阴虚型卵巢储备功能下降患者子宫动脉血流参数及激素的影响,以临床指标及临床症状证实调经汤对DOR的有效性。方法:将符合临床及实验室诊断标准的、中医辨证为肾阴虚证型DOR患者70例平均随机分配作为实验组及对照组,行经阴道彩色多普勒超声检查,观察子宫动脉收缩期峰值流速(PSV),舒张末期流速(EDV),阻力指数(RI)等,抽血化验血清雌二醇(E2)及FSH水平,实验组给予激素补充药芬吗通+中药调经汤治疗,对照组只给西药予芬吗通治疗。结果:治疗后:两组血清激素水平及子宫动脉血流动力学参数比较有统计学意义(P<0.05)。且治疗组治疗后临床症状改善情况明显优于对照组。结论:激素及子宫动脉血流参数等指标的改变可证明西药激素补充治疗+中药调经汤对肾阴虚DOR治疗效果明显,并可明显改善临床症状,可推广其在临床应用。
OBJECTIVE: To observe the effects of Hormone Suotong Tong + Tiaojing Decoction on uterine arterial blood flow parameters and hormones in patients with deficiency of kidney yin deficiency, and to confirm the validity of Tiaojing Decoction for DOR by clinical indicators and clinical symptoms. Methods: According to clinical and laboratory diagnostic criteria, 70 cases of TCM syndrome differentiation of kidney yin deficiency type DOR were randomly assigned to experimental group and control group. Vaginal color Doppler ultrasonography was performed to observe the peak systolic velocity of uterine artery (PSV), end-diastolic velocity (EDV), resistance index (RI), blood samples were collected for serum estradiol (E2) and FSH levels. To the western medicine to Finnish treatment. Results: After treatment, the level of serum hormone and uterine artery hemodynamics parameters were statistically significant (P <0.05). The improvement of clinical symptoms in the treatment group was obviously better than that in the control group. Conclusion: Hormone and uterine arterial blood flow parameters and other indicators of changes can prove that Western medicine hormone therapy + traditional Chinese medicine Tiaojing Decoction treatment of kidney yin obvious effect, and can significantly improve the clinical symptoms, can promote its clinical application.