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目的了解江西省鄱阳湖区血吸虫病防治方法及其效果。方法检索中国生物医学文献数据库及PubMed数据库中的相关文献,按相应纳入排除标准进行筛选后,进行文献计量学及Meta分析。结果共91篇文献纳入分析。其中有关化疗效果、流行病学调查及策略研究、健康教育的文献分别为19、17、14篇。应用蒿甲醚预防血吸虫感染研究的Meta分析显示RR值为0.07,95%可信区间为0.03～0.15。选择性化疗和全民化疗在防治效果上无明显差异,但前者使感染率下降1%的费用是后者的63.67%。健康教育对学生及妇女干预效果明显,可使学生疫水接触率降至0。结论鄱阳湖区血吸虫病防治方法多样,效果明显。今后应加强综合防治措施及效果评价方面的研究,并提高科研设计的质量。
Objective To understand the methods of prevention and treatment of schistosomiasis in Poyang Lake of Jiangxi Province and its effects. Methods The relevant literature from China Biomedical Literature Database and PubMed database was searched and bibliometrically analyzed according to the inclusion criteria. Results A total of 91 articles were included in the analysis. Among them, there were 19,17,14 articles about the effect of chemotherapy, epidemiological investigation and strategy research, and health education respectively. Meta-analysis of studies on the prevention of schistosomiasis with artemether showed a RR of 0.07 and a 95% confidence interval of 0.03 to 0.15. Selective chemotherapy and universal chemotherapy in the control effect no significant difference, but the former makes the infection rate of 1% reduction is 63.67% of the latter. The effect of health education on students and women is obvious, which can reduce the contact rate of students to water. Conclusion There are many ways to prevent and cure schistosomiasis in Poyang Lake, and the results are obvious. In the future, research on comprehensive prevention and control measures and effect evaluation should be strengthened and the quality of scientific research and design improved.