患者男性,39岁。4年前发现鼻下部和左脸肿胀,经抗炎治疗2～3天肿胀很快消失。半年后左侧鼻唇沟处再次肿胀、搔痒,皮肤表面有毛刺样物,挤压时可将毛刺样物挤出,经抗炎治疗无明显改善,病变缓慢扩大,并在上唇和右鼻旁出现新的类似病变。1年半前在当地医院做左鼻旁皮肤活 Male patient, 39 years old. 4 years ago found that the bottom of the nose and left face swelling, anti-inflammatory treatment of 2 to 3 days swollen quickly disappear. Six months after the left nasolabial fold at the swelling, itching, burr-like surface of the skin samples can squeeze the burr sample extrusion, no significant improvement by anti-inflammatory treatment, the lesion slowly expanded, and in the upper lip and right nasal A new similar disease appears. A year and a half ago at the local hospital left nasal paralysis of the skin