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目的 :对比分析对超高龄胃癌患者进行保守治疗与手术治疗的效果。方法 :将2012年11月至2015年6月某院收治的50例超高龄胃癌患者作为研究对象,将其随机分为手术组与保守组,每组各25例患者。对保守组患者进行保守治疗,对手术组患者进行手术治疗,在2个月后对比分析两组患者的临床疗效及发生并发症的情况。结果 :手术组患者在进行治疗后其病情的缓解率高于保守组患者,差异有统计学意义(P<0.05)。与进行治疗前相比,手术组中手术成功的患者与保守组患者进行治疗后其VAS评分均较低,差异有统计学意义(P<0.05)。与手术组中手术未成功的患者相比,保守组患者的VAS评分较低,差异有统计学意义(P<0.05)。与保守组患者相比,手术组患者进行治疗后其QOL评分较低,其并发症的发生率较高,差异有统计学意义(P<0.05)。结论 :与进行保守治疗相比,对超高龄胃癌患者进行手术治疗可更有效地控制其病情,但更易使其发生并发症,而且可降低其生活质量。
Objective: To comparatively analyze the effect of conservative treatment and surgical treatment of patients with advanced gastric cancer. Methods: Fifty patients with super-advanced gastric cancer who were admitted to a hospital from November 2012 to June 2015 were randomly divided into operation group and conservative group, with 25 patients in each group. Patients in the conservative group were treated conservatively and surgically treated in the surgery group. The clinical efficacy and complications of the two groups were compared after 2 months. Results: The remission rate of patients in operation group after treatment was higher than that in conservative group, the difference was statistically significant (P <0.05). Compared with those before treatment, the VAS scores of patients in operation group and patients in conservative group were lower after operation, the difference was statistically significant (P <0.05). The VAS scores of patients in the conservative group were lower than those in the surgery group who did not succeed in surgery, the difference was statistically significant (P <0.05). Compared with the conservative group, the patients in the operation group had lower QOL scores and higher incidence of complications, the difference was statistically significant (P <0.05). CONCLUSIONS: Surgical treatment of patients with advanced gastric cancer is more effective than conservative treatment in the management of patients with advanced gastric cancer but is more likely to cause complications and lower the quality of life.