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目的 探讨腹腔化疗对肝癌伴张力性腹水的疗效。方法 晚期肝癌伴张力性腹水患者 6 1例 ,随机分三组 ,A组 2 6例采用腹水超滤浓缩自体腹腔回输联合腹腔内化疗 ;B组 18例采用治疗性放腹水联合腔内化疗 ;C组 17例单纯治疗性放腹水。B超测定患者治疗前后腹水消退情况。结果 一疗程有效率为 :A组 5 7 7% ;B组4 4 4 % ;C组 11 9%。腹水超滤浓缩自体腹腔回输联合腹腔化疗明显改善患者营养状况、肾功能、肾钠排泄及血浆肾素 -血管紧张素 -醛固酮代谢。结论 腹腔化疗对于肝癌伴张力性腹水具有一定的疗效 ,腹水超滤浓缩自体腹腔回输联合腹腔内化疗是治疗肝癌伴张力性腹水的一种安全、可靠、经济的方法
Objective To investigate the effect of intraperitoneal chemotherapy on hepatocellular carcinoma with tension ascites. Methods Twenty-six patients with advanced hepatocellular carcinoma and tension ascites were randomly divided into three groups. A group of 26 patients received ascites ultrafiltration and autologous intraperitoneal chemotherapy combined with intraperitoneal chemotherapy. In group B, 18 patients received therapeutic combination of ascites and endovascular chemotherapy. C group of 17 cases of simple ascitic fluid. B-measured before and after treatment in patients with ascites regression. Results A course of treatment efficiency: A group 57.7%; B group 44.4%; C group 11 9%. Ascites ultrafiltration concentration of autologous abdominal combined with intraperitoneal chemotherapy significantly improved nutritional status, renal function, renal sodium excretion and plasma renin - angiotensin - aldosterone metabolism. Conclusion Intraperitoneal chemotherapy has a certain effect on hepatocellular carcinoma with tension ascites. Ascites ultrafiltration and autologous intraabdominal chemotherapy combined with intraperitoneal chemotherapy is a safe, reliable and economical method for the treatment of hepatocellular carcinoma with tension ascites.