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目的初步观察和探索经皮肾交感神经射频消融术治疗顽固性高血压的疗效及操作方法。方法对3例顽固性高血压患者实施经皮肾交感神经射频消融术并随访半年至一年,观察其血压及用药水平的变化。结果术后患者的血压较术前明显下降,降压药物种类及剂量亦减少。随访结果显示3例患者的高血压药物使用剂量和种类均有减少,其中2例患者血压控制在目标水平,1例未达到目标水平。结论顽固性高血压患者通过经皮肾交感神经射频消融术可以得到的血压持续下降,用药剂量和种类减少的益处。
Objective To observe and explore the efficacy and operation of percutaneous renal sympathetic nerve radiofrequency ablation for refractory hypertension. Methods Percutaneous renal sympathetic nerve radiofrequency ablation was performed in 3 patients with refractory hypertension and followed up for half a year to one year. The changes of blood pressure and medication level were observed. Results Postoperative patients’ blood pressure decreased significantly compared with that before operation, and the type and dose of antihypertensive drugs also decreased. The follow-up results showed that the dosage and type of hypertension medication decreased in 3 patients, of which 2 patients were controlled at the target level and 1 patient did not reach the target level. CONCLUSIONS: Percutaneous renal sympathetic nerve radiofrequency ablation of refractory hypertension continues to lead to a decrease in blood pressure, dose and type of benefit.