硝苯吡啶(Nifedipine)是一种钙拮抗剂。这类药物常用于解除动脉痉挛,并发现其有松弛肠道平滑肌痉挛的作用,对食管失弛缓可能有效。本文报道硝苯吡啶对改善食管失弛缓患者食管下端括约肌(LES)压力和临床症状的研究。测压研究:受试者为20例经食管测压、X线和内窥镜检查证实的,属Adams等分类第1～2期(即不包括须作手术等治疗之失代偿期)的食管失弛缓患者。男性 Nifedipine is a calcium antagonist. These drugs are commonly used to relieve arterial spasm and found to have the effect of relaxing spasm of the intestine, which may be effective in ameliorating esophageal atrophy. This article reports the study of nifedipine in improving the esophageal lower esophageal sphincter (LES) pressure and clinical symptoms. Manometry study: Subjects were 20 esophageal manometry, X-ray and endoscopy confirmed, is Adams and other categories of 1 to 2 (that is not including the need for surgery and other decompensated) Esophageal atrophy patients. male