论文部分内容阅读
(www.colorcon.com)使用基于Kollicoat~174;IR的一种开发中的高效速释薄膜包衣系统,研究水性包衣固含量对颜色均匀度、外观以及片剂表面光滑度的影响。为评价这一开发中的高效速释薄膜包衣系统的性能,将其与基于聚乙烯醇(PVA)的欧巴代~174;Ⅱ(Opadry~174;Ⅱ)高性能薄膜包衣系统进行比较。1方法1.1包衣液黏度以20%~35%的固含量配制基于Kollicoat~174;IR的全配方包衣系统的水分散体,使用DV-Ⅱ+Pro黏度计(布鲁克
(www.colorcon.com) A developing high-speed, fast-release film coating system based on Kollicoat® 1744; IR was used to study the effect of aqueous coating solids content on color uniformity, appearance, and tablet surface smoothness. In order to evaluate the performance of this developed high-speed immediate release film coating system, the high performance film coating system based on polyvinyl alcohol (PVA) from Opadry ~ 174; Ⅱ (Opadry ~ 174; Ⅱ) Compare. 1 Method 1.1 Coating Fluid Viscosity Aqueous dispersions based on Kollicoat ~ 174; IR complete formulation coating system were formulated at 20% ~ 35% solids using a DV-II + Pro viscometer