目的:探讨分隔膜密闭式输液接头在人工肝治疗血管通路封管中的应用。方法:将68例行人工肝治疗的患者随机分为对照组33例使用普通肝素帽进行股静脉血管通路封管和实验组35例使用分隔膜密闭式输液接头进行股静脉血管通路封管。结果:对照组发生股静脉血管通路堵管4例,实验组无股静脉血管通路堵管,p<0.05。结论:在人工肝治疗血管通路封管中使用分隔膜密闭式输液接头能明显降低血管通路的堵管率。 Objective: To investigate the application of the septum-sealed infusion connector in the sealing of vascular access by artificial liver. Methods: A total of 68 patients treated with artificial liver were randomly divided into control group (n = 33), heparin occlusion capillaries (n = 35) and femoral vein occlusion group (n = 35) Results: There were 4 cases of femoral vein occlusion in the control group and no femoral vein occlusion in the experimental group (p <0.05). Conclusion: The use of septum-sealed infusion tubes in the sealing of vascular access tubes by artificial liver can significantly reduce the rate of occlusion of vascular access.