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综述和讨论了 NO·的自由基性质和生理功能.NO·分子轨道上有一个未成对电子,是一个典型的自由基,它的半寿期为6—50s,反应性极强,遇氧反应生成另一个自由基 NO_2,可以和超氧阴离子反应生成氧化性极强的超氧亚硝基阴离子(ONOO~-).NO·与一些重要生物功能有关,它是内皮细胞松弛因子,可使血管平滑肌松弛,防止血小板凝聚.细胞免疫活化和组织缺血再灌注也产生 NO·.它还和神经传导及光接受器的信号发射等有关.
The free radical nature and physiological functions of NO · are summarized and discussed.No · has an unpaired electron on the molecular orbital and is a typical free radical with a half-life of 6-50 s and high reactivity, Generate another free radical NO 2, which can react with superoxide anion to generate highly oxidative superoxide nitroso anion (ONOO ~ -) NO · is related to some important biological functions, it is an endothelial cell relaxing factor, Smooth muscle relaxation, prevent platelet aggregation.Cellular immune activation and tissue ischemia-reperfusion also produce NO · It also and nerve conduction and photoreceptor signaling and so on.