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目的:探讨复方丹参注射液联合阿奇霉素间歇给药治疗小儿支原体肺炎的临床疗效。方法:选取我院收治的56例支原体肺炎患儿作为研究对象,随机均分为实验组和对照组,对照组采用阿奇霉素间歇给药法治疗,实验组在对照组的基础上采用阿奇霉素间歇给药联合复方丹参注射液治疗,比较2组的临床症状消失时间及不良反应发生率。结果:实验组总有效率为96.43%;对照组为78.57%,2组总有效率比较有显著性差异(P<0.05);实验组临床症状消失时间相比于对照组显著缩短,比较有显著性差异(P<0.05);分别接受治疗后,实验组出现不良反应2例,对照组出现不良反应6例,实验组不良反应发生率明显低于对照组。结论:采用复方丹参注射液联合阿奇霉素间歇给药治疗小儿支原体肺炎能显著缩短患儿临床症状消失时间,在治疗小儿支原体肺炎方面疗效显著,值得在临床上进一步应用。
Objective: To investigate the clinical efficacy of compound Salvia miltiorrhiza injection combined with intermittent azithromycin in the treatment of Mycoplasma pneumonia in children. Methods: 56 children with Mycoplasma pneumonia admitted in our hospital were randomly divided into experimental group and control group. The control group was treated with intermittent azithromycin treatment. The experimental group was treated with azithromycin intermittently on the basis of the control group Combined with Salvia miltiorrhiza injection, the disappearance of clinical symptoms and the incidence of adverse reactions were compared between the two groups. Results: The total effective rate was 96.43% in the experimental group and 78.57% in the control group. The total effective rate in the two groups was significantly different (P <0.05). The disappearance time of clinical symptoms in the experimental group was significantly shorter than that in the control group (P <0.05). After treatment, there were 2 adverse reactions in the experimental group and 6 adverse reactions in the control group. The incidence of adverse reactions in the experimental group was significantly lower than that in the control group. Conclusion: The combination of compound Salvia miltiorrhiza injection and intermittent azithromycin treatment of children with mycoplasma pneumonia can significantly shorten the disappearance of clinical symptoms in children, in the treatment of children with mycoplasma pneumonia significant effect, it is worth further clinical application.