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目的调查深圳入境旅客基孔肯雅病毒感染情况,初步对入境旅客传入基孔肯雅病毒进行风险评估。方法采用基于入境旅客血清流行病学调查方法 (现况调查),以ELISA法检测目标人群血清特异性IgM及IgG抗体,检出阳性则进一步以RT-PCR检测病毒核酸以确诊,以此评估入境旅客的感染情况。结果共收集到深圳口岸截获发热旅客的血清154份,入境体检旅客血清293份。发热旅客基孔肯雅病毒IgG抗体阳性率为5.2%,体检旅客基孔肯雅病毒IgG抗体阳性率为4.4%。对抗体检测阳性血清进行RT-PCR检测,未发现核酸阳性病例。结论所调查的入境旅客中,基孔肯雅病毒特异性IgG抗体总体阳性率为4.7%,大多数人是来自疫区,因此,通过旅客将基孔肯雅热传入我国的风险较高。
Objective To investigate the status of Chikungunya virus inbound tourists in Shenzhen and to assess the risk of Chikungunya virus inbound travelers. Methods Serum-specific IgM and IgG antibodies of target population were detected by serological epidemiological investigation based on inbound passenger (current status survey), and positive samples were further detected by RT-PCR to confirm the presence of viral nucleic acid Passenger infection. Results A total of 154 intercepted sera from Shenzhen port and 293 sera from inbound tourists were collected. The positive rate of Chikungunya virus IgG in fever travelers was 5.2%, and the positive rate of Chikungunya virus IgG in health check-ups was 4.4%. Antibody detection of positive serum for RT-PCR detection, no nucleic acid positive cases were found. Conclusions The overall positive rate of Chikungunya virus-specific IgG antibodies among the surveyed arrivals was 4.7%, with most of them coming from endemic areas. Therefore, there is a high risk of passing Chikungunya into our country through travelers.